Tasso and partners receive $4.25M to develop a universal surveillance platform for infectious disease outbreaks

MANASSAS, Va. — September 28, 2017 — Tasso, Inc. (Tasso), Ceres Nanosciences (Ceres), George Mason University (Mason), and the United States Army Medical Research Institute of Infectious Diseases (USAMRIID) today announced the commencement of an $11.7 million program, funded by the Defense Threat Reduction Agency (DTRA), to develop a reliable, safe, and simple universal surveillance platform for infectious disease outbreaks. During this multi-year program, which will be initiated with $4.25 million in funding from DTRA, Ceres will integrate its Nanotrap® particle technology, which can capture, concentrate, and preserve pathogens and other biomolecules, into Tasso’s HemoLink™ device for simple and painless collection of large-volume capillary blood samples in remote environments.

Tasso and Ceres will work in close collaboration with infectious disease experts and advanced biodefense laboratories at Mason and USAMRIID to develop an effective disease surveillance platform that can be rapidly deployed in the field, operated by untrained users, and improve early response. The platform will combine the Nanotrap® and HemoLink™ technologies to safely and reproducibly collect, preserve, and transport blood-borne pathogens.

“Infectious diseases remain one of the main causes of death worldwide and a significant threat to national security,” said Dr. Kylene Kehn-Hall of Mason. “In just the last five years, for example, epidemics of Ebola, Chikungunya, and Zika viruses, usually restricted to tropical climates, have reached the United States.”

“When a new outbreak occurs, public health officials quickly need as much information as possible about the pathogen(s) causing the outbreak to determine how to control it,” said Dr. Louis Altamura of USAMRIID. “Analyzing clinical samples from infected patients is one of the best ways to get that information, but existing blood sample collection and screening methods can expose healthcare workers and laboratory technicians to pathogens, presenting safety concerns for these workers and potentially contributing to the spread of the epidemic.”

“We have demonstrated already that Nanotrap® particles can be used to enrich pathogens like influenza from biological samples and stabilize them for improved downstream analysis,” said Ben Lepene, CTO of Ceres Nanosciences. “We’re very excited to work with Tasso, Mason, and USAMRIID to apply that same approach to enrich and stabilize from blood a wide range of host biomarkers along with viral and bacterial pathogens that represent a risk to the U.S. Department of Defense.”

“There is an urgent need for an easier way to reach people in rural or hard-to-reach environments to provide health experts with the information they need to make effective decisions in a timely manner. Integrating the Nanotrap® particle technology and the simple HemoLink™ blood collection technology will enable acquiring samples from populations in outbreak regions without putting phlebotomists or patients at risk or requiring burdensome logistical networks,” said Dr. Erwin Berthier, VP of R&D at Tasso. “The integrated device will be rapidly and safely deployable in any environment and will collect a large volume of capillary blood that can be shipped over long distances while retaining its clinical relevance.”

About Tasso, Inc.
Tasso is a Seattle, WA, based startup focusing on improving healthcare and the diagnostics process by developing more accessible and convenient blood collection and shipping methods that can reach people in any location or environment. Tasso originated from technology developed in the University of Wisconsin-Madison and assembles a highly qualified team of biomedical engineers, hematology researchers, human-factor designers, and clinical experts that have successfully developed the HemoLink. The HemoLink was developed with funding from the National Institute for Minority Health and Health Disparities (NIMHD) and the Defense Advanced Research Projects Agency (DARPA). Tasso is an open and collaborative company that focuses on working with leading technological and clinical partners to deliver reliable and disruptive diagnostic innovations. Learn more at www.tassoinc.com

Press Contact:
Ben Casavant
Tasso, Inc.
262-323-1415
ben@tassoinc.com

About Ceres Nanosciences, Inc.
Ceres Nanosciences is a privately held company, located in Prince William County, Virginia, focused on the development of research and diagnostic products using its unique and proprietary Nanotrap® particle technology. The Nanotrap® particle technology provides powerful biomarker capture and biofluid sample processing capabilities for a wide array of diagnostic applications and sample handling needs. The Nanotrap® particle technology was invented at George Mason University and developed under funding from the National Institutes of Health (NIH). With support from the NIH, the Defense Advanced Research Projects Agency (DARPA), the Bill and Melinda Gates Foundation, and the Commonwealth of Virginia, Ceres is focused on incorporating this technology into a range of innovative diagnostic products. 

Press Contact:
Ross M. Dunlap
Ceres Nanosciences, Inc.
1.800.615.0418 ext. 202
rdunlap@ceresnano.com

About George Mason University
George Mason University is Virginia’s largest public research university. Located near Washington, D.C., Mason enrolls more than 36,000 students from 130 countries and all 50 states. Mason has grown rapidly over the past half-century and is recognized for its innovation and entrepreneurship, remarkable diversity, and commitment to accessibility. Mason is also one of the best values in higher education, producing graduates who lead all Virginia schools with the highest annual salaries. George Mason University's National Center for Biodefense and Infectious Diseases is a $50 million, 52,000-square-foot, stand-alone, high-security facility located adjacent to GMU’s Prince William Campus in Manassas, Virginia. The facility features more than 18,500 square feet of lab space comprising BSL-2 open-design laboratories with cell culture suites, preparation areas, and a microscopy room; ABSL-2 rooms, a surgery suite; BSL-3 laboratories; and ABSL-3 suites and a necropsy suite. The facility is fully approved and licensed for select agent work by the Centers for Disease Control and Prevention (CDC) and the U.S. Department of Agriculture (USDA).

Press Contact:
Michele McDonald
George Mason University
703-993-3779
mmcdon15@gmu.edu 

About USAMRIID
USAMRIID’s mission is to provide leading edge medical capabilities to deter and defend against current and emerging biological threat agents. Research conducted at USAMRIID leads to medical solutions—vaccines, drugs, diagnostics, and information—that benefit both military personnel and civilians. The Institute plays a key role as the lead military medical research laboratory for the Defense Threat Reduction Agency’s Joint Science and Technology Office for Chemical and Biological Defense. USAMRIID is a subordinate laboratory of the U.S. Army Medical Research and Materiel Command. For more information, visit www.usamriid.army.mil. [The information contained in this press release does not necessarily reflect the position or the policy of the Government and no official endorsement should be inferred.]

Press Contact:
Caree Vander Linden
U.S. Army Medical Research Institute of Infectious Diseases
301.619.2285
teresa.l.vanderlinden.civ@mail.mil

Tasso simplifies blood draws, awarded $3M expansion

ADISON, Wis., April 7, 2015 /PRNewswire/ -- 

Tasso, Inc., a medtech start-up developing the HemoLink™, a small disposable device to simplify blood sampling, has secured an additional $2.9M in grant funding to advance its HemoLink technology with its development partner GenTegra LLC.

Based on progress made in developing the HemoLink, the Defense Advanced Research Projects Agency (DARPA) has expanded Tasso's ongoing Phase II SBIR contract. Tasso and GenTegra are developing an integrated device that is able to collect blood from patients and stabilize biomarkers at ambient temperatures without requiring cold chain transportation. The stabilization component of the grant is a $1.3M allocation to GenTegra LLC, whose Matrix Chaperone™ technology is redefining the boundaries of ambient sample stabilization.

Dr. Erwin Berthier, VP of Tasso and principal investigator on the contract, emphasized, "This is a disruptive technology that will enable connecting anyone in the world - from home, rural areas, low resource locations, or war zones - to a centralized blood analysis laboratory, providing affordable cutting edge diagnostics to everyone."

The HemoLink device safely collects blood from the surface of the skin, effectively replacing the need for venipuncture across a broad number of diagnostic tests.  The Matrix Chaperone stabilizes biospecimens at a broad range of ambient temperatures in order to preserve the vast diagnostic data offered by a blood sample. This combination of disruptive technologies fundamentally changes the way blood testing is done, replacing hospital-centric testing with testing focused on the user. Tasso President, Ben Moga states, "Together, this powerful HemoLink-Matrix Chaperone combination will modernize the diagnostic process by providing superior and affordable 'in home' and 'point of care' access to healthcare."

Bruce Jamieson, CEO of GenTegra, offers, "GenTegra is pleased to be working with the innovative HemoLink device that Tasso is developing as an alternative to venipuncture blood collection. As a part of the HemoLink device our stabilization chemistry, Matrix Chaperone, stabilizes the blood in dry form for convenient shipping and any queue time at the clinical lab while waiting for diagnostic testing. The temperature range that is protected coincides with commercial carriers' specifications, enabling the shipment of specimens in a simple mailer - free from cold chain requirements. The combination of a simple blood collection device and stabilization of the specimen at ambient temperatures will open many possibilities for new innovative 'in home' and 'point-of-care' sample collection scenarios."

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Tasso, Inc. simplifies blood sampling, secures $2.3M

MADISON, Wis., Feb. 3, 2014 /PRNewswire/ -- 

Tasso, Inc., a medtech start-up developing a wearable blood draw device, has secured $2.3M in grant funding for its HemoLink­™ technology.

After a successful SBIR Phase I, the Defense Advanced Research Projects Agency has granted the company an additional $1.75M in a Phase II effort to demonstrate large volume sample acquisition from the capillary bed. The NIH, National Institute on Minority Health and Health Disparities, has also granted the company a Phase I SBIR of $400k in an effort to provide better health care for underprivileged populations.

Professor David Beebe, recently named to the board of directors, comments, "Tasso has generated data that demonstrates a 200 microliter blood draw with a proprietary microfluidic platform. This is a significant achievement in the field of blood sample acquisition and I am excited about its potential for collecting even larger volumes."

With the R&D effort advancing at full steam, the company has turned its eye toward commercialization of the technology. Ms. Dominique Freeman, a seasoned Medical Device and Life Sciences executive, has been recruited to the board of directors. Additionally, Mr. Benjamin Moga will expand his role from Chairman of the Board to lead commercial efforts as President.

"We have compelling data, a motivated management team, and an unmet clinical need in a growing market," says Mr. Moga. "Expanding home care by enabling safe and convenient blood draws for clinical diagnosis and monitoring is exactly the kind of innovation that improves outcomes without raising healthcare costs."

SOURCE Tasso, Inc.